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  • 标题:The effect of fibronectin-coated implant on canine osseointegration
  • 本地全文:下载
  • 作者:Kim, Sungtae ; Myung, Woo-Chun ; Lee, Jung-Seok
  • 期刊名称:The Journal of the Korean Academy of Periodontology
  • 印刷版ISSN:0250-3352
  • 出版年度:2011
  • 卷号:41
  • 期号:5
  • 页码:242-247
  • DOI:10.5051/jpis.2011.41.5.242
  • 语种:English
  • 出版社:Korean Academy of Periodontology
  • 摘要:Purpose

    The purpose of this study was to characterize the osseointegration of the fibronectin-coated implant surface.

    Methods

    Sand-blasted, large-grit, acid-etched (SLA) surface implants, with or without a thin calcium phosphate and fibronectin coating, were placed in edentulous mandibles of dogs 8 weeks after extraction. All dogs were sacrificed forhistological and histomorphometric evaluation after 4- and 8-week healing periods.

    Results

    All types of implants were clinically stable without any mobility. Although the bone-to-implant contact and bone density of the SLA implants coated with calcium phosphate (CaP)/fibronectin were lower than the uncoated SLA implants, there were no significant differences between the uncoated SLA surface group and the SLA surface coated with CaP/fibronectin group.

    Conclusions

    Within the limits of this study, SLA surfaces coated with CaP/fibronectin were shown to have comparable bone-to-implant contact and bone density to uncoated SLA surfaces.

  • 关键词:Biocompatible coated materials; Bone Density; Calcium phosphate; Dental implants; Fibronectins
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