Attachment level was changed from 8.67±1.72mm to 7.00±1.60mm (control); from 8.93±2.23mm to 6.00±1.92mm (test); and bone probing depth was decreased from 10.20±1.90mm to 9.07±1.95mm (control); from 10.14±2.14mm to 7.43±2.06mm (test).

This study indicates that treatment of periodontal intrabony defects with EMD is clinically superior to treatment without EMD (OFD alone) in every parameter evaluated. Within the limits of this study, the application of EMD in intrabony defects resulted in clinically significant gain of clinical attachment level and decrease of bone probing depth. And further controlled clinical studies are required to confirm the effectiveness of the EMD in the treatment of various osseous defects.