If bone grafts and guided tissue regeneration are effective individually in treating osseous defects, then the question is, what would happen when they are combined. Bone grafts using Calcium Carbonate(Biocoral) and Guided Tissue Regeneration using Calcium Sulfate(CALMATRIX) will maximize their advantages and show the best clinical results in intrabony defects. This study was to compare the effects of a combination of CS and CC with control treated only with modified widman flap in a periodontal repair of intrabony defects.

30 patients with chronic periodontitis were used in this study. 10 patients were treated with a combination of CS and CC as the experimental groupII and another 10 patients were treated with CC as the experimental groupI, and the remaining 10 patients, the control group were treated only with modified widman flap. Clinical parameters including probing depth, gingival recession, bone probing depth and loss of attachment were recorded 6 months later.

The probing depth changes were 3.30±1.34 mm in the control group, 4.2±1.55 mm in the experimental groupI(CC) and 5.00±1.33 mm in the experimental groupII(CS+CC). They all showed a significant decrease 6 months after surgery( p <0.01). There was a significant difference( p <0.05) between the control and experimental group. However there were no significant difference( p <0.05) between the experimental groupIand II. The gingival recession changes w -1.30±1.25 mm in the control group, This is a significant difference( p <0.01). However, there was a -0.50±0.53 mm change in the experimental groupI(CC) and -0.60±0.97 mm in the experimental groupII(CS+CC). In addition, in terms of gingival recession, there was a no significance difference( p <0.05) among the groups. The clinical attachment level changes were 2.00±1.33 mm in the control group, 3.60±1.58 mm in the experimental groupI(CC) and 4.40±1.17 mm in the experimental groupII(CS+CC). They all showed a significant decrease 6 months after surgery( p <0.01). There was a significant difference( p <0.05) between the control and experimental group. However there was a no significance difference( p <0.05) between the experimental groupI andII. The bone probing depth changes were 0.60±0.52 mm in the control group, 3.20±1.48 mm in the experimental groupI (CC) and 4.60±1.43 mm in the experimental groupII(CS+CC). All of them showed a significant decrease 6 months after surgery( p <0.01), there was a significance difference( p <0.05) among the groups.

Treatment using a combination of CS and CC have a potential to improve periodontal parameters in intrabony defects and More efficient clinical results can be expected in intrabony defects less than 2 walls grafted with CS and CC.