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  • 标题:Bone Health and Clinical Results after Hip Fracture Surgery in Patients with Subclinical Hypothyroidism
  • 本地全文:下载
  • 作者:Kim, Ki-Choul ; Lee, Young-Kyun ; Lee, You Jin
  • 期刊名称:Journal of Bone Metabolism
  • 印刷版ISSN:2287-6375
  • 出版年度:2014
  • 卷号:21
  • 期号:3
  • 页码:213-216
  • DOI:10.11005/jbm.2014.21.3.213
  • 语种:English
  • 出版社:The Korean Society for Bone and Mineral Research
  • 摘要:Background

    Subclinical thyroid dysfunction might influence a bone health. We evaluated whether subclinical hypothyroidism adversely affects bone health including bone mineral density (BMD), level of vitamin D, and bone turnover status in patients with hip fracture.

    Methods

    We evaluated 471 patients aged 50 years or older, who underwent hip fracture surgeries. BMD, level of vitamin D, bone turnover status, and one-year mortality were compared between subclinical hypothyroidism group and control group.

    Results

    BMD of femur and the level of 25-hydroxy-vitamin D (25-[OH]D) were similar in the two groups. There were no significant differences in bone turnover markers according to thyroid function. No significant differences were observed between the groups in utilization of intensive care unit (ICU), length of hospital stay, mobility, and one-year mortality.

    Conclusions

    Subclinical hypothyroidism was not associated with reduced bone health, including BMD, the level of 25-(OH)D, and bone turnover marker.

  • 关键词:Bone Density; Fractures bone; Hip fractures; Hypothyroidism
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