摘要:Purpose: This paper attempts to highlight the significant role of organizational DNA in improving Organizational Performance (OP). Research Design/Methodology: Using Booz Allen Hamilton, 2002; Neilson, et al., 2003; 2004; Booz, 2004; Neilson, et al., 2005; Holoday, 2005; Remecker & Bowdin, 2005; Neilson, 2006; Vanmullem & Hondeghem, 2007; Soroush, et al., 2013 of organizational DNA, the study develops a number of hypotheses and tests them. This research is an applied form in terms of its goals and descriptive in terms of the method of data collection. Three groups of employees at industrial companies were examined. Of the 372 questionnaires that were distributed, 300 usable questionnaires were returned, a response rate of 81%. Findings: This study reveals that the four building blocks of organizational DNA (organizational structure, decision rights, motivators, and information) have a significantly direct effect on OP. Practical implications: The study suggests that the industrial companies can improve OP by influencing its organizational DNA, specifically, by developing the organizational structure, decision rights, motivators, and information. The study provided a set of recommendations including the necessity to pay more attention to the dimensions of organizational DNA as of a key source for organizations to enhance the competitive advantage which is of prime significance for OP. Originality/value: The study observes that there is a critical shortage of studying organizational DNA in Egypt and that a greater understanding of the factors that influence the OP, including organizational structure, decision rights, motivators, and information, is of great importance. Therefore, this study is to examine the relationship between organizational DNA and OP among employees in industrial companies in Egypt.