文章基本信息
- 标题：Antiretroviral therapy with three nucleoside reverse transcriptase inhibitors in treatment-naive HIV-infected patients in Abidjan (Cote d’Ivoire)
- 本地全文：下载
- 作者：F.B. Sako ; J. Zoungrana ; J.P. Dembélé 等
- 期刊名称：Médecine et Santé Tropicales
- 印刷版ISSN：1157-5999
- 电子版ISSN：1950-6953
- 出版年度：2012
- 卷号：22
- 期号：3
- 页码：333-334
- DOI：10.1684/mst.2012.0092
- 出版社：John Libbey Eurotext
- 摘要：Authors F.B. Sako , J. Zoungrana , J.P. Dembélé , N.A. Kassi , S.I. Ouattara Service des maladies infectieuses et tropicales, CHU de Treichville, Abidjan, Côte d’Ivoire Key words: antiretroviral treatment, nucleoside analog reverse transcriptase inhibitors, HIV, Côte d’Ivoire DOI : 10.1684/mst.2012.0092 Page(s) : 333-4 Published in: 2012
This study assesses the results of initial antiretroviral therapy with 3 nucleoside reverse transcriptase inhibitors over the first 12 months of treatment.
Patients’ general health improved significantly during the year, with a significant mean weight gain (from 59.3 kg to 65.12 kg) and a strong regression in the frequency of opportunistic infections over the study period, from 38% to 2% (P<0.0001). The mean CD4 T-cell count rose from 242.8 to 390.5 cell/mm 3, for a mean increase of 147.7 cells/mm 3.
Accordingly, antiretroviral treatment with three nucleoside reverse transcriptase inhibitors is effective and is a useful alternative in a country with limited resources.
- 关键词：antiretroviral treatment; nucleoside analog reverse transcriptase inhibitors; HIV; Côte d’Ivoire
