摘要:Authors E.F. Ka , M.M. Cisse , A.T. Lemrabott , S. Fall , M. Diallo , S. Diallo , M. Faye , A. Niang , B. Diouf Service de néphrologie,, Service de médecine interne,, Service de dermatologie,, Service de rhumatologie, Hôpital Aristide-Le-Dantec, 30 avenue Pasteur, 3001 Dakar, Sénégal Key words: lupus, nephropathy, Senegal DOI : 10.1684/mst.2013.0200 Page(s) : 328-31 Published in: 2013 This study sought to assess the prevalence of lupus nephropathy and to determine its clinical, histological, therapeutic and outcome profiles. Patients and methods. This retrospective study examined records covering a 10-year period from 1999 to 2009 at the nephrology department of the Aristide Le Dantec University Hospital Center. Results. The records showed 43 patients with systemic lupus erythematosus (SLE), and 72% had lupus nephritis. The patients’ mean age was 32.9 years; 40 were women and 3 men, for a sex ratio of 0.075. The lupus nephritis led to discovery of SLE in 27.9%. The mean proteinuria concentration was 2.01 g/dL. Seventeen patients had impaired renal function, and 26 had renal biopsies. It found class II nephritis in 2 patients, class IV in 10, and class V in 12. In addition, fifteen patients received combined corticosteroid + immunosuppressant treatment. Four patients died during the study period, one from SLE activity, two from complications of renal failure, and the fourth from sepsis. Conclusion. A larger study would be useful to assess more acurately the prevalence of various classes and severity of lupus nephropathy among blacks living in sub-Saharan Africa.