期刊名称：Revue de Neuropsychologie Neurosciences Cognitives et Cliniques
印刷版ISSN：2101-6739
电子版ISSN：2102-6025
出版年度：2010
卷号：2
期号：1
页码：38-45
DOI：10.1684/nrp.2010.0056
出版社：John Libbey Eurotext
摘要：Authors Danielle David , Olivier Moreaud , Annik Charnallet Unité de neuropsychologie et CMRR, Pôle de psychiatrie et neurologie, CHU de Grenoble, BP 217, 38043 Grenoble Cedex 09, Laboratoire de psychologie et neurocognition, LPNC CNRS UMR 5105 Key words: progressive aphasia, semantic dementia DOI : 10.1684/nrp.2010.0056 Page(s) : 38-45 Published in: 2010 Among frontotemporal lobar degeneration syndromes, there is a debate between two very similar entities, progressive fluent aphasia (PFA) and semantic dementia (SD). Typically, the diagnosis of SD relies on an isolated and progressive loss of semantic knowledge, showing itself in visual identification disorders and in an anomia with impaired single word comprehension, without any phonological and syntaxic impairment. PFA is caracterized by similar language disorders but without any visual identification deficits. According to some authors, PFA could be a subtype of DS, visual identification disorder appearing later in the course. In both cases, language disorders would originate from a semantic impairment. In this paper, we present a case study of a patient, HD, presenting a PFA and we propose an alternative hypothesis, the progressive impairment of his phonological lexicon, to explain his language disorders.
