期刊名称：Revue de Neuropsychologie Neurosciences Cognitives et Cliniques
印刷版ISSN：2101-6739
电子版ISSN：2102-6025
出版年度：2012
卷号：4
期号：3
页码：151-162
DOI：10.1684/nrp.2012.0230
出版社：John Libbey Eurotext
摘要：Figures See all figures Authors Martine Fischer , Françoise Lekeu , Anne Quittre , Catherine Olivier , Vinciane Wojtasik , Daniel Gillain , Mickaël Hiligsmann , Eric Salmon Centre de la mémoire, CHU de Liège Centre-Ville, quai Godefroid Kurth, 45, 4020 Liège, Belgique, Service d’informations médico-économiques (SIME), CHU de Liège, B35 Sart Tilman, 4000 Liège, Belgique, Département de santé publique, d’épidémiologie et d’économie de la santé, université de Liège, avenue de l’Hôpital 3, B23, 4000 Liège, Belgique Key words: dementia, Alzheimer's disease, cost-utility analysis, cognitive rehabilitation, cost effectiveness DOI : 10.1684/nrp.2012.0230 Page(s) : 151-62 Published in: 2012 Cognitive rehabilitation for patients with early Alzheimer's disease aims to help the patient performing a specific task bypassing the operating deficits while using residual cognitive abilities. To date, no economic evaluation has yet demonstrated the efficiency of this type of care. We have included in this study 17 patients with early degenerative dementia. Nine have received cognitive rehabilitation in addition to pharmacological treatment and eight were treated only by medication. The follow up was fixed at the rate of a quarterly visit to the informal caregiver, at 3, 6, 9 and 12 months to collect the direct costs related to the disease and implement a questionnaire to assess utility values related to the treatment. Participants were enrolled sequentially over our study period of 15 months. 17 subjects were followed for 3 months, 12 for 6 months, 6 to 9 months and 3 for one year. The results of the cost-utility analysis at three months to six months follow-up suggest that cognitive rehabilitation is efficient for the patient and source of savings for health insurance and a health perspective overall. The analysis of nine and twelve months was not possible due to small sample sizes. Although there are many limitations to the study, these initial results suggest an economic interest of cognitive rehabilitation that needs to be confirmed by studies on larger populations.
