期刊名称：Revue de Neuropsychologie Neurosciences Cognitives et Cliniques
印刷版ISSN：2101-6739
电子版ISSN：2102-6025
出版年度：2013
卷号：5
期号：3
页码：213-222
DOI：10.1684/nrp.2013.0273
出版社：John Libbey Eurotext
摘要：Figures See all figures Authors Mathieu Lesourd , Didier Le Gall , Josselin Baumard , Bernard Croisile , Christophe Jarry , François Osiurak Laboratoire d’étude des mécanismes cognitifs (EA 3082), université Lyon 2, 5, avenue Pierre-Mendès-France, 69676 Bron cedex, France, Service de neuropsychologie, hôpital neurologique Pierre Wertheimer, 59, boulevard Pinel, 69677 Bron Cedex, France, Laboratoire de psychologie des Pays de la Loire (EA 4638), université d’Angers, 5, bis boulevard Lavoisier, 49045 Angers Cedex, France, Unité de neuropsychologie, département de neurologie, centre hospitalier universitaire d’Angers, 4, rue Larrey, 49000 Angers Cedex 9, France Key words: apraxia, Alzheimer's disease, transitive gestures, intransitive gestures DOI : 10.1684/nrp.2013.0273 Page(s) : 213-22 Published in: 2013 Alzheimer's disease is characterized by the progressive impairment of cognitive functions. Whereas the study of amnesia, aphasia, agnosia and dysexecutive impairments to a lesser extent has been well documented, apraxia has received little attention [1]. The aim of this review is to fill this gap by presenting an overview of the praxis impairment, which typically appears in the course of the disease. This review focuses on transitive gestures (i.e., tool use tasks) and intransitive gestures (i.e., symbolic and meaningless). On the basis of these results, we propose interpretations as to the nature of the underlying mechanisms impaired by the disease. Finally, we provide some answers to help clinicians to better understand and assess the apraxic disorders in Alzheimer's disease.
