摘要：Las enterobacterias son los microorganismos etiologicos mas frecuentemente asociados a las infecciones nosocomiales (in), caracterizandose por su alta resistencia a los antibioticos B-lactamicos, mediada por la produccion de B-lactamasas de Espectro Extendido (blee). Su uso excesivo aumenta la seleccion de cepas multirresistentes, favoreciendo su propagacion e incremento de las complicaciones de casos de in. En algunos casos las cepas productoras de blee presentan resistencia adicional a aminoglucosidos, quinolonas, tetraciclinas y trimetoprim-sulfametoxazol, reduciendo las opciones terapeuticas de las in. Con la finalidad de conocer localmente la magnitud de este problema, se estudiaron 87 cepas de enterobacterias aisladas de casos de in, encontrandose que el 26.43% son productoras de blee y en este caso fenotipicamente multirresistentes.
其他摘要：Enterobacteria are the most frequent etiologic agents of nosocomial infections (ni). Many of the strains involved are resistant to beta-lactam antimicrobials since they produce B-lactamases, and in a growing number of cases they produce extended-spectrum B-lactamases (esbl). The excessive use of â-lactam antimicrobials increases the selection of multiresistant strains, favoring their spread. The strains producing esbl may present additional resistance to aminoglycosides, quinolones, tetracyclines, and trimethoprimsulfamethoxazole, thus reducing therapeutic alternatives. With the purpose of searching the extent of this problem locally, 87 strains of enterobacteria were analyzed. It turned out to be that 26.43% were esbl producers and some of the strains were also resistant to non-lactamic antibiotics.
