The present study was carried in order to evaluate the effect of saline water irrigation with electrical conductivity (ECw) of 0.5; 1.5; 3.0; 4.5 and 6.0 dS m-1, on germination and some growth variables during the seedling formation process of four guava cultivars (Psidium guajava L.): Pentecoste, Paluma, Surubim and IPA B-38. Water salinity inhibited the germination process, plant height, stem diameter, leaf area and dry matter production of roots, stems and leaves, independently of cultivar. After germination, the seedlings did not survive due to saline water effects of ECw 4.5 and 6.0 dS m-1. After 180 days of sowing, the seedlings irrigated with ECw more than 1.5 dS m-1 did not present agronomic quality for planting. Dry matter production sequence of different parts of plants was as follows: leaves > roots > stems, without significant differences among cultivars especially when irrigated with saline water of ECw > 3.0 dS m-1.