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  • 标题:Human albumin use at hospitals in the Metropolitan Region of Rio de Janeiro, Brazil
  • 本地全文:下载
  • 作者:Matos, Guacira Corrêa de ; Rozenfeld, Suely ; Martins, Monica
  • 期刊名称:Cadernos de Saúde Pública
  • 印刷版ISSN:0102-311X
  • 电子版ISSN:1678-4464
  • 出版年度:2010
  • 卷号:26
  • 期号:5
  • 页码:981-990
  • DOI:10.1590/S0102-311X2010000500020
  • 语种:English
  • 出版社:Escola Nacional de Saúde Pública,Fundação Oswaldo Cruz
  • 摘要:

    The study analyzes the use of human albumin in hospitals in Rio de Janeiro, Brazil, using inpatient data from the information system of Brazil's health system between 1999 and 2001. Death was the main outcome as patients died in 32% of admissions in which human albumin was used as compared with 4% of all admissions in the same period and region. The Charlson Comorbidity Index was included for risk adjustment. Human albumin was used in 10,111 in-patients more than 1 year old. 87,774 50-ml bottles of 20% human albumin were consumed at a cost of US$ 1,755. The main diagnoses were neoplasms (29.1%), diseases of the digestive system (17.5%) and circulatory system (16%). Death rate increased with age, public ownership of the hospital, clinical services (as opposed to surgical services), length of stay and use of intensive care. Death was associated with use of more than four bottles of human albumin (PR: 1.30; 99%CI: 1.23-1.37), adjusted for severity and speciality. The results are cause for concern as they may be related to poor compliance with guidelines, excess of risk to patients and unnecessary expenses for the public health system.

  • 关键词:Albumina Sérica;Uso de Medicamentos;Farmacoepidemiologia;Avaliação de Serviços de Saúde
  • 其他关键词:Serum Albumin;Drug Utilization;Pharmacoepidemiology;Health Services Evaluation
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