Studies dedicated to examination of self-regulation posit a bi-directional association between self-regulation and other variables including social connectedness, self-efficacy and self-control. However, to date, studies of this caliber have only evidenced that self-regulation is a predictor of other variables. In the present study, the factors that predict self-regulation are examined among 209 undergraduate students in their preparatory year in the University of Dammam, Saudi Arabia. Collection of data was conducted in the school year’s second semester. Based on the results, significant positive relations exist between social connectedness, self-efficacy and self-control, with self-regulation. Moreover, the results revealed that social connectedness and self-control are predictors of students’ self-regulation, but not self-efficacy. Added to this, the result revealed a significant difference in the relationship between self-control and self-regulation among female students, with the other variables insignificant for both genders. Hence, it can be stated that higher education practitioners and academicians may focus on the assessment and the development of the students’ skills in terms of self-regulation.