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  • 标题:Comparative Evaluation of Carbamates as Prophylactic Agents against Organophosphate Intoxication Rats
  • 本地全文:下载
  • 作者:A. K. Chatterjee
  • 期刊名称:Defence Science Journal
  • 印刷版ISSN:0976-464X
  • 出版年度:2013
  • 卷号:42
  • 期号:2
  • 页码:85-87
  • DOI:10.14429/dsj.42.4354
  • 语种:English
  • 出版社:Defence Scientific Information & Documentation Centre
  • 摘要:Investigates the effects of two well-known carbamates, physostigmine and pyridostigmine against organophosphorous compound and nerve gas toxicity. Physostigmine pretreatment for 30 min enhanced the survival time of rats against DFP intoxication whereas it did not have any effect with sarin poisoning. However, pyridostigmine pretreatment did not produce any significant effect on survival time either against DFP or sarin intoxication. Treatment with atropine along with carbamates further enhanced significantly the survival time against DFP poisoning.
  • 关键词:Carbamates ;Physostigmine;Pyridostigmine;Nerve gas toxicity;DFP poisoning
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