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文章基本信息

  • 标题:Immunotoxicology: Modulation of the Immune System by Xenobiotics
  • 本地全文:下载
  • 作者:Prakash S. Nagarkatti ; Mitzi Nagarkatti
  • 期刊名称:Defence Science Journal
  • 印刷版ISSN:0976-464X
  • 出版年度:2014
  • 卷号:37
  • 期号:2
  • 页码:235-244
  • DOI:10.14429/dsj.37.5904
  • 语种:English
  • 出版社:Defence Scientific Information & Documentation Centre
  • 摘要:Starting wih a definition of immunity, this review describes general mechanisms by which immune system is modulated and details several immunotoxicological screening methods to assess the immumologic and host resistance alterations following chemical exposure. Among a variety of immuno toxic compounds known, only four representative compounds namely o-chloro benzylidine malononitrile (CS), 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), chloroquine, 1,3 bis (2-chloroethyl) 1-nitrosourea (BCNU) have been chosen for an elaborate discussion.
  • 关键词:Immunotoxicological screening;Immune system;Immunity
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