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  • 标题:Synthesis of p-(Di-n-propylsulphamyl) Benzoic Acid
  • 本地全文:下载
  • 作者:S. K. Shukla ; Govind Rai Chaudhry
  • 期刊名称:Defence Science Journal
  • 印刷版ISSN:0976-464X
  • 出版年度:2014
  • 卷号:18
  • 期号:4
  • 页码:239-240
  • DOI:10.14429/dsj.18.7458
  • 语种:English
  • 出版社:Defence Scientific Information & Documentation Centre
  • 摘要:A process for the synthesis of p-carboxybenzene sulphonylchloride by oxidation of toluene-p-sulphonylchloride as well as toluene-p-sulphonic acid has been developed. p-carboxybenzene sulphonylchloride on condensation with di-n-propylamine yield p-(di-n-propylsulphamyl) -benzoic acid, an uricusuric agent employed in chronic gouty arthritis and used as an antiuric adjuvant known in trade as "Benemid, Probenecid".
  • 关键词:Penicillin;Benemid Probenecid;Chronic Gouty Arthritis
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