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  • 标题:Evaluation of the predictive capability of an in-vitro model of colonisation resistance to Clostridium difficile infection
  • 本地全文:下载
  • 作者:S. P. Borriello ; F. E. Barclay ; A. R. Welch
  • 期刊名称:Microbial Ecology in Health and Disease
  • 印刷版ISSN:1651-2235
  • 出版年度:1988
  • 卷号:1
  • 期号:1
  • DOI:10.3402/mehd.v1i1.7394
  • 语种:English
  • 出版社:Microbial Ecology in Health and Disease
  • 摘要:Caecal emulsions prepared from hamsters pre-treated with clindamycin or ampicillin supported growth of, and cytotoxin production by, Clostridium difficile, whereas those from aztreonam or temocillin pre-treated or untreated hamsters did not. These findings were predictive of outcome of infection with C. difficile as clindamycin and ampicillin pre-treated animals became colonized and died whereas the other animals did not.Keywords: Colonisation resistance; C. difficile; Antibiotic-associated colitis.
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