摘要：Epidermis contains high amounts of IL-1. However, it is not clear whether IL-1 is a normal constituent of the epidermis or whether it is induced by continuous environmental stimulation of normal skin flora. These results show that the germ-free mouse epidermis contains IL-1 activity indicating that IL-1 is a normal constituent of this tissue. No difference in epidermal IL-1 activity was observed between the germ-free and the holoxenic mice.Keywords: Skin flora; Hairless mice; Interleukin 1; Axenic.
