摘要：Bacterial genome nucleotide sequencing has revolutionized genetic, biochemical and molecular biology research on bacteria and, indeed, many higher organisms. Over the past decade, the sequences of more than 500 bacterial genomes have become available in the public domain. Considerable emphasis was initially placed on sequence determination of the genomes of pathogenic bacteria, including food-borne pathogens. However, in recent years, genome sequencing of gastrointestinal tract (GIT) commensals and symbionts, as well as food-grade bacteria, has become more established among sequencing projects, currently represented by large efforts made in the genome decoding of typical GIT commensal microorganisms such as bifidobacteria.
