摘要：Objectives. Increasing type 2 diabetes in Aboriginal communities across North America raisesconcerns about metabolic syndrome in these populations. Some prevalence information for AmericanIndians exists, but little has been available for Canada’s First Nations. Study Design. Wescreened 60 % of the eligible population of a single First Nation in Alberta for diabetes, prediabetes,cardiovascular risk, and metabolic syndrome.Methods. NCEP/ATP III and IDF criteria were used to identify metabolic syndrome in participantsaged ≥ 18; modified NCEP/ATP III criteria were used for participants aged < 18. Logisticregression identified factors associated with the metabolic syndrome.Results. 297 individuals were screened (176 adults, 84 children/adolescents, with complete data).52.3 % of adults had metabolic syndrome using NCEP/ATP III criteria, and 50 % using IDFcriteria. 40.5 % of individuals aged < 18 had the condition. Waist circumference was the mostprevalent correlate. Bivariate analysis suggested that age, BMI, weight, A1c, LDL-C, ADA riskscore and activity pattern were associated with metabolic syndrome.Conclusions. Our data represent the first available for Western Cree and are consistent withprevalence reported for Aboriginal populations in Ontario and Manitoba. High rates of obesity,pre-diabetes and metabolic syndrome for participants aged < 18 raise concerns about future prevalenceof diabetes and cardiovascular disease.Keywords: Aboriginal, North America, risk factors, metabolic syndrome X, insulin resistance,cardiovascular diseases, type 2 diabetes mellitus(Int J Circumpolar Health 2006;65(5):389-402.)
关键词：Aboriginal, North America, risk factors, metabolic syndrome X, insulin resistance,cardiovascular diseases, type 2 diabetes mellitus
