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  • 标题:Bactome II: Analyzing Gene List for Gene Ontology Over-Representation
  • 其他标题:Bactome II: Analyzing Gene List for Gene Ontology Over-Representation
  • 本地全文:下载
  • 期刊名称:The Python Papers Source Codes
  • 电子版ISSN:1836-621X
  • 出版年度:2011
  • 卷号:3
  • 页码:3
  • 语种:English
  • 出版社:The Python Papers Anthology
  • 摘要:Microarray is an experimental tool that allows for the screening of several thousand genes in a single experiment and the analysis of which often requires mapping onto biological processes. This allows for the examination of processes that are over-represented. A number of tools have been developed but each differed in terms of organisms that can be analyzed (not sure what you mean here). Gene Ontology website has a list of up-to-date annotation files for different organisms that can be used for over-representation analysis. Each file maps each gene of the organism to its ontological terms. It is a simple tool that allows users to use the up-to-date annotation files to generate the expected and observed counts for each GO identifier (GO ID) from a given gene list for further statistical analyses.
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