1.SIFAT HIPOGLIKEMIK DAN HIPOKOLESTEROLEMIK PROTEIN KEDELAI PADA TIKUS MODEL TOLERANSI GLUKOSA TERGANGGU (TGT) INDUKSI ALLOKSAN 1) [Hypoglycemic and Hypocholesterolemic Activities of Soy Protein on Impared Glucose Intolerant Rats Induced by Alloxan] Masun Lasimo 2 ) , Zuheid Noor 3) , dan Y. Marsono 3) 1) Makalah dipresentasikan pada Seminar Nasional PATPI, Semarang 9-10 Oktober 2001 2) PascasarjanaIlmu dan Teknologi Pangan UGM - Yogyakarta 3) Fakultas Teknologi Pertanian UGM - Yogyakarta ABSTRACT Previous studies indicated that soy protein had hypoglycemic and hypocholesterolemic activity in induced diabetic rats. However when combined with different sources of carbohydrate, the effects were not known yet. The purpose of this research was to evaluate the hypogylcemic and hypocholesterolemic properties of soy protein combined with cornstarch or wheat flour, on four groups of impaired glucose tolerance (IGT) alloxan induced male Wistar rats models. During the first two weeks, rats were given high fat and cholesterol diet to induce hypercholesterolemic. On the third week, rats were injected with alloxan 60 mg/kg body weight to induce hyperglycemia, and in the following three weeks each group was given one of the following, casein+cornstach (CC), soy protein+cornstarch (SC), casein+wheat flour (CW), or soy protein +wheat flour (SW). The glucose and lipid concentrations of blood of individual rat were measured before and, 1st , 7th, 14th, and 21th day after the injection of alloxan. The results showed that the soy protein diets have hypoglycemic and hypocholestrolemic activity as compared to casein diets. The different source of carbohydrate diet affected hypocholesterolemic property of soy protein, but did not affect hypoglycemic property. It seems that the SC diet decreases glucose concentration more than the SW diet (17,45% and 7,04% from baseline, respectively). The SC diet had more ability to decrease total and LDL cholesterol (9,52% and 21, 89% from baseline, respectively), while the SW diet had more ability to decrease triglycerides (24,64% from baseline). Key words: Soy protein, hypoglycemic, hypocholesterolemic, impaired glucose tolerance (IGT) and alloxan induced

作　　者：Masun Lasimo ;Zuheid Noor ;Y. Marsono

出　　处：Jurnal Teknologi Dan Industri Pangan. 2002 ;13(2):136.doi:10.6066/4341

出版社：Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

文章 ID：100029207

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2.SIFAT HIPOGLIKEMIK DAN HIPOKOLESTEROLEMIK PROTEIN KEDELAI PADA TIKUS MODEL TOLERANSI GLUKOSA TERGANGGU (TGT) INDUKSI ALLOKSAN 1) [Hypoglycemic and Hypocholesterolemic Activities of Soy Protein on Impared Glucose Intolerant Rats Induced by Alloxan]

作　　者：Masun Lasimo ;Zuheid Noor ;Y. Marsono

出　　处：Jurnal Teknologi Dan Industri Pangan. 2012 ;13(2):136.

出版社：Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

文章 ID：185575454

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