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作 者：Elmeizy Arafah ;Deddy Muchtadi ;Fransiska R Zakaria 等
出 处：Jurnal Teknologi Dan Industri Pangan. 2004 ;15(3):214.doi:10.6066/584
出 版 社：Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI
文 章 ID：100029190
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作 者：Heri Winarsi ;Deddy Muchtadi ;Fransiska R Zakaria 等
出 处：Jurnal Teknologi Dan Industri Pangan. 2004 ;15(1):28.doi:10.6066/534
出 版 社：Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI
文 章 ID：100029244
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作 者：Hery Winarsi ;Deddy Muchtadi ;Fransiska R Zakaria 等
出 处：Jurnal Teknologi Dan Industri Pangan. 2004 ;15(3):179.doi:10.6066/574
出 版 社：Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI
文 章 ID：100029257
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作 者：Fransiska R Zakaria ;Hari Susanto ;Arif Hartoyo
出 处：Jurnal Teknologi Dan Industri Pangan. 2000 ;11(1):36.doi:10.6066/920
出 版 社：Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI
文 章 ID：100029272
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PENGARUH EKSTRAK JAMU TERHADAP AKTIVITAS SEL NATURAL KILLER DALAM MELISIS ALUR SEL LEUKIMIA (K-562) SECARA IN VITRO [The Effects of Commercial “Jamu” Extracts on Natural Killer Cell Activity in Lysing Leukemic Cell Line (K-562 ) in vitro]Fransiska R. Zakaria 1) , dan Elisa Veronica D.C. 2) 1) Jurusan Teknologi Pangan dan Gizi, Fateta-IPB 2) Alumni Jurusan Teknologi Pangan dan Gizi, Fateta-IPB ABSTRACT Natural killer (NK) cell consitutes white blood cells which specifically functions in lysing tumor and virus invected cells. In this research, a commercial “Jamu” was tested to observe its effect on NK cells activity against leukemic cell lines (K562) in vitro. Jamu was extracted with hot water, diluted and added into cell cultures consisted of a mixture of human peripheric limphocyte cells, as the source of the effector NK cells, and K562 cell line i.e., the target cells which were cell line derived from human leukemia and had been labelled with H3-thymidine. The mixture of the cells were made by culturing the two cells at the ratio of 50:1 and 100 : 1, respectively. The results showed that lysing activity of NK cells in the presence of “Jamu” water extract measured as lysing percentage and lysing index increased only slightly, which were not statiscally significant. It should be considered that the test used in this research represents only a part of the lysing mechanism by NK cells against the target cells. An in vivo test for a period of time will be recessary to elucidate ffurther this NK cell activity. Key words : “ Natural Killer” Cell, Leucemic, Cell Line, and “jamu“ extracts
作 者：Fransiska R. Zakaria ;Elisa Veronica D.C.
出 处：Jurnal Teknologi Dan Industri Pangan. 2002 ;12(1):19.doi:10.6066/7019
出 版 社：Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI
文 章 ID：100029323
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AKTIVITAS STIMULASI KOMPONEN BIOAKTIF RIMPANG JAHE (Zingiber officinale Roscoe) PADA SEL LIMFOSIT B MANUSIA SECARA IN VITRO [Effects of Bioactive Compounds of Ginger (Zingiber officinale Roscoe) Root on B Cell Lymphocyte Function using In Vitro System] Tejasari 1), Fransiska R Zakaria 2) , dan Dondin Sajuthi 3) 1) Staf Pengajar Fakultas Teknologi Pertanian, Universitas Jember 2) Staf Pengajar Jurusan Teknologi Pangan dan Gizi, Fateta-IPB 3) Peneliti Pada Pusat Studi Satwa Primata IPB ABSTRACT The effect of two fractions of oleoresin compounds from ginger root on lymphocyte function were studied by observing B cell proliferations, which were measured by the incorporation of 3H-thymidine during cell incubation. The doses of oleoresin compounds and its two fractions tested were 50,100, 150, and 200 mg per ml. Lymphocyte from human peripheral blood were isolated using ficoll density gradient technique, and cultured in the presence of the compounds in RPMI-1640 medium for 4 days, with or without the addition of 3 mM paraquat as the oxidizing agent. The results showed that the effects of oleoresin and its two fractions depended on its doses. Oleoresin and its two fractions increased B cell proliferation with the highest activity of 456 percent at low dose of 50 mg per ml. These result showed a positive effect of oleoresin compound and its two fractions on B cell functions at low doses. It indicated that bioactive compounds of ginger root at low concentration have positive effects on humoral immune response and this supports the traditional belief that ginger increases body resistance to common cold. Key words : bioactive compound, proliferation, humoral immune responds, stress oxidative, in vitro, and lymphocyte
作 者：. Tejasari ;Fransiska R Zakaria ;Dondin Sajuthi
出 处：Jurnal Teknologi Dan Industri Pangan. 2002 ;12(1):47.doi:10.6066/7024
出 版 社：Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI
文 章 ID：100029345
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AKTIVITAS ANTIOKSIDAN EKSTRAK DIKHLOROMETANA DAN AIR JAHE (Zingiber officinale Roscoe) PADA ASAM LINOLEAT [Antioxidant Activity of Ginger (Zingiber officinale Roscoe) Dichloromethane and Water Exctract on Linoleic Acid] Aisyah Tri Septiana 1) , Deddy Muchtadi 2) dan Fransiska R. Zakaria 2) 1) Jurusan Teknologi Pertanian, Fakultas Pertanian, UNSOED Purwokerto 2) Program Studi Ilmu Pangan, Fakultas Teknologi Pertanian, IPB-Bogor ABSTRACT Antioxidant activity of various ginger extracts are different. The aims of this work are to determine the antioxidant activity of ginger extracts on linoleic acid. The antioxidant activities were tested on linoleic acid supplemented with water and dichloromethane extract of ginger. The antioxidant activity was tested by measuring malonaldehide absorbance. Total phenol and iron content of the extracts were analyzed by spectrometry. This research showed that antioxidant activity of water and dichloromethane extract of ginger was stronger than a-tocopherol, and antioxidant activity of dichloromethane extract is stronger than water extract of ginger. Antioxidant activity of ginger extracts, seems to be correlated with the total phenol and iron contents. Key words : Antioxidant, linoleic acid, dichloromethane, malonaldehide, and extract of ginger.
作 者：Aisyah Tri Septiana ;Deddy Muchtadi ;Fransiska R. Zakaria
出 处：Jurnal Teknologi Dan Industri Pangan. 2002 ;13(2):105.doi:10.6066/4336
出 版 社：Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI
文 章 ID：100029493
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作 者：Endang Prangdimurti ;Deddy Muchtadi ;Made Astawan 等
出 处：Jurnal Teknologi Dan Industri Pangan. 2006 ;17(2):79.doi:10.6066/420
出 版 社：Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI
文 章 ID：100029513
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作 者：Waysima Waysima ;Ujang Sumarwan ;Ali Khomsan 等
出 处：Jurnal Ilmu Keluarga & Konsumen. 2011 ;4(1):74-81.
出 版 社：Jurnal Ilmu Keluarga & Konsumen
文 章 ID：99977413
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作 者：Erniati ;Fransiska R. Zakaria ;Bambang Pontjo Priosoeryanto
出 处：Jurnal Teknologi Dan Industri Pangan. 2012 ;23(1):81.doi:10.6066/5299
出 版 社：Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI
文 章 ID：101251087
